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HNF1B基因位于17號染色體,含有9個外顯子,編碼肝細(xì)胞核因子1β(hepatocyte nuclear factor 1β,HNF1β)。HNF1β為含有同源結(jié)構(gòu)域的轉(zhuǎn)錄因子超家族中的一員,在胰腺、腎臟、腸道、肝臟、生殖道等多種器官起著重要的組織特異性調(diào)控基因表達(dá)的作用,同時也參與了這些器官的胚胎發(fā)育。
產(chǎn)品詳情:
別名:HNF1beta, LFB3, MODY5, TCF2, VHNF1
類型:多克隆抗體
來源:Rabbit IgG
應(yīng)用: IHC,WB,ICC-IF
反應(yīng)種屬:human
免疫原:Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQH
緩沖液組成:40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
應(yīng)用實例:
Immunohistochemical staining of human renal cancer shows moderate to strong nuclear positivity in tumorl cells.
WB analysis in human kidney tissue.
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm. Antibody staining is shown in green.
訂購信息:
產(chǎn)品名稱 | 貨號 | 規(guī)格 |
Anti-HNF1B Antibody | HPA002083 | 100ul |
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