The 16-10A1 monoclonal antibody reacts with mouse CD80 also known as B7-1. CD80 is a 60 kDa Ig superfamily member and is expressed by activated B cells and constitutively by monocytes and dendritic cells. This ligand binds to CD28 to provide a costimulatory signal necessary for T cell activation and survival, and cytokine production. Additionally, CD80 binds to CTLA-4 which inhibits T cells. This antibody has been shown to block CD80 in vivo.

產(chǎn)品名稱:InVivoMab anti-mouse CD80 (B7-1)

反應(yīng)種屬:mouse

宿主來源:Armenian hamster

實驗應(yīng)用:In vivo CD80 blockade, Flow cytometry

同種型:IgG2

免疫原:CHO cell line transfected with mouse CD80

克隆性:Monoclonal

克隆號:16-10A1

產(chǎn)品濃度:Lot specific,typically between 4-11 mg/ml

保存溫度:Undiluted at 4°C in the dark

運(yùn)輸溫度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

預(yù)期分子量:150 kDa

產(chǎn)品形式:液體

有效期:One year from the date of receipt if stored as recommended

產(chǎn)地:美國

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